Five teenage girls (Stacy Owino, Cynthia Otieno, Purity Achieng,
The group of girls calls themselves ‘The Restorers’, and they were the only Africans that participated in the 2017 Technovation Challenge in Silicon Valley in August. The Restorers did not win the Technovation Challenge, but they will continue their fight against FGM and hope to get i-Cut into the Google Play Store soon.
I know the journey won’t always be easy but to the girls who dream of being an engineer or an entrepreneur and who dream of creating amazing things, I want you to know that there’s a place for you in this industry, there’s a place for you at Google—don’t let anyone tell you otherwise, Google CEO Sundar Pichai told the girls.
“This app a good way of getting people to talk about FGM,” said Dorcas Adhiambo Owino, the group’s mentor and Kenya’s Technovation program lead.
The app will help connect affected girls to legal and medical assistance. Girls who are forced to undergo the procedure can also alert local authorities by pressing a panic button on the app, CNN reports.
FGM, a non-medical procedure that involves the total or partial removal of a woman’s external genitalia, is illegal in Kenya. But it’s still practiced because of its cultural significance as a rite of passage and prerequisite for marriage.
According to a 2016 Unicef report, one in five girls have undergone the procedure in the east African nation. The practice is mostly done when the girls are between the ages 10-14 years

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KPV is a naturally occurring tripeptide consisting of the amino
acids Lysine, Proline, and Valine, derived from α-melanocyte-stimulating
hormone (α-MSH). Extensively recognized for its vital anti-inflammatory, immunomodulatory, and antimicrobial properties, KPV has shown remarkable therapeutic potential in managing quite so
much of inflammatory and autoimmune circumstances.
Preclinical and clinical analysis has additional illustrated its ability to promote accelerated wound healing,
improve pores and skin health, and scale back scar formation.
Α‐Melanocyte‐stimulating hormone (α‐MSH) is a tridecapeptide derived from the proopiomelanocortin by post‐translational processing.
In addition to its effects on melanocytes, α‐MSH has potent anti‐inflammatory effects when administered systemically or regionally.
By choosing a KPV peptide that has been lab tested like Biaxol, you can feel confident that you are using
a safe and effective product. By No Means disregard skilled medical recommendation or delay in in search of it because of one thing you have learn on this web site.
I am 21 years or older and understand that the merchandise
listed on this site are for research functions only.
Store ALL Peptide Stacks from Direct Peptides at present, your trusted supplier of premium scientific grade peptides online.
Growing Older pores and skin experiences collagen breakdown, oxidative stress, and moisture loss.
Peptides like KPV and GHK-Cu are being studied for his or her capacity to
counteract these results. You can attain our customer service
team via our contact page on the web site or by emailing us at We are here to help you with any questions or concerns you may have.
Prior to his professorship, Dr. Marinov practiced preventative, evidence-based medicine with an emphasis on Nutrition and Dietetics.
He is extensively revealed in international peer-reviewed scientific
journals and focuses on peptide therapy analysis. That stated, as with any research peptide, long-term research are
needed before it can be considered for therapeutic use.
Researchers are continuing to evaluate its effectiveness, dosage, and interactions
with other compounds to make sure its security and efficacy.
Let our skilled staff guide you with integrity, science, and care.
KPV and BPC-157 are powerful tools on the earth of regenerative drugs.
They provide thrilling potential for healing, restoration, and resilience—but they aren’t with out risks or unknowns.
Since KPV peptide is strictly for research functions,
there aren’t any permitted human applications. Nevertheless, research suggest it has a robust safety profile, with minimal danger of toxicity or irritation in laboratory settings.
It entails coagulation, inflammation, proliferation, and reworking.
KPV peptide helps at a quantity of factors in this
process, making it an important subject in regenerative medicine.
Our peptides are meant for analysis purposes solely and
are not for human consumption. All of our peptides are examined for quality and purity and meet
the usual for utilization. The Recovery Code
Method is usually utilized in research to study anti-aging, therapeutic, and
tissue regeneration processes.
It works amazingly properly topically for skin irritations – bug bites, scalp points
(most are fungal related). As I talked about within the CerebroPep section, we don’t use mind dietary
supplements later in the day because they’ll intervene with sleep.
If you haven’t learn the CerebroPep section immediately above, I suggest beginning there as a end result of the mind portion of this peptide is the same.
It’s very efficient at clearing damaged tissue and can restore damage from toxins you’ve been uncovered
to, even in the past. It works very quickly so if you see nothing the
primary day, regulate your dose upward. I examine it as an choice to calm mast cells if nothing else worked.
KPV, with its anti-inflammatory and anti-microbial properties,
may be very useful for combatting these microbes and therapeutic wounds (Böhm M, 2019).
The greater dose of KPV (100 μM) used in our in vivo
research was based on previous studies using α-MSH to treat experimental colitis (28, 29) and
was chosen to extend the probabilities of KPV to achieve mouse colon. Since
our in vitro research showed that PepT1 has a very excessive affinity for KPV, it is rather likely that
KPV is transported into infected colonic cells even whether it is current at decrease concentrations.
Though the results of KPV are pretty particular and in a narrow range, it
still has a systemic application within the human physique.
Appears like KPV and BPC-157 are the two leaders in relation to using peptides
for enhancing overall intestine health (likely through
the decreased manufacturing of pro-inflammatory compounds).
KPV is a tripeptide (i.e. three amino acids long) that makes up
the C-terminal end of a bigger naturally occurring melanocortin peptide hormone in your physique often known as alpha-melanocyte-stimulating
hormone (α-MSH). Finally, this text accommodates
a substantial quantity of data that can inform you- the patient and
can even inform your doctor. It is not data that is supposed to diagnose or
deal with sufferers who’ve inflammatory bowel illness.
One study(5) was conducted on a cell tradition of infected intestinal cells.
The primary function of this examine was to determine the peptide’s potential in opposition to inflammation. Infected intestinal cells had been isolated and
exposed to both the KPV peptide or a placebo.
Upon publicity to the peptide, these cells were examined, and results indicated that even nanomolar
concentrations of the peptide appeared to have led to anti-inflammatory outcomes.
The researchers suggested that the KPV peptide appeared
to primarily act by way of PepT1 expression in these intestinal cells, suggesting that PepT1 may play a
role in transporting the peptide to the site
of irritation. GHK-Cu peptide, in distinction, is renowned for exciting collagen and elastin synthesis, that
are important for preserving pores and skin agency and youthful.
Α‐MSH clearly inhibits the nuclear translocalisation of the lively p65/p50
NF‐κB heterodimer. In HDMEC, KP and KPV additionally slightly cut
back migration of NF‐κB, while K(D)PT has the most pronounced impact.
In KC it can be seen that the octamer MSH6–13 reduces nuclear translocalisation of NF‐κB, while the pentamer MSH9–13, which lacks many
of the described melanocortin receptor‐binding area of α‐MSH, has almost no impact.
The dipeptide KP however has a pronounced inhibitory effect, whereas PV once more has not, indicating a sure importance of the lysine residue.
We then investigated the anti-inflammatory impact of KPV in TNBS-induced mouse colitis model forty eight hours after its administration. Addition of KPV within the ingesting water considerably reduced weight loss at day one and two compared with mice that obtained TNBS alone (Figure 8A).
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